The estrogen receptor-α A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study

INTRODUCTION: Evidence suggests that alterations in estrogen signaling pathways, including estrogen receptor-α (ER-α), occur during breast cancer development. A point mutation in ER-α (nucleotide A908G), producing an amino acid change from lysine to arginine at codon 303 (K303R) results in receptor...

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Detalhes bibliográficos
Main Authors: Conway, Kathleen, Parrish, Eloise, Edmiston, Sharon N, Tolbert, Dawn, Tse, Chiu-Kit, Geradts, Joseph, Livasy, Chad A, Singh, Harsharan, Newman, Beth, Millikan, Robert C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410768/
https://ncbi.nlm.nih.gov/pubmed/16280033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1315
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