25-Hydroxyvitamin D(3 )1α-hydroxylase expression in breast cancer and use of non-1α-hydroxylated vitamin D analogue

INTRODUCTION: The cytochrome P450 mitochondrial enzyme 25-hydroxyvitamin D(3 )1α-hydroxylase (1α-hydroxylase) of renal tubule cells hydroxylates the major circulating form of vitamin D (25(OH)D(3)) to the active systemic hormone 1,25(OH)(2)D(3). Local production of 1,25(OH)(2)D(3 )appears to occur a...

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Main Authors: Segersten, Ulrika, Holm, Pernille Kaae, Björklund, Peyman, Hessman, Ola, Nordgren, Hans, Binderup, Lise, Åkerström, Göran, Hellman, Per, Westin, Gunnar
格式: Artigo
語言:Inglês
出版: BioMed Central 2005
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410765/
https://ncbi.nlm.nih.gov/pubmed/16280049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1332
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