Antisense oligonucleotides targeting the progesterone receptor inhibit hormone-independent breast cancer growth in mice

INTRODUCTION: Previous data from our laboratory suggested that progesterone receptors (PRs) are involved in progestin-independent growth of mammary carcinomas. To investigate this possibility further, we studied the effects of PR antisense oligodeoxynucleotides (asPR) on in vivo tumor growth. METHOD...

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Main Authors: Lamb, Caroline A, Helguero, Luisa A, Giulianelli, Sebastián, Soldati, Rocío, Vanzulli, Silvia I, Molinolo, Alfredo, Lanari, Claudia
格式: Artigo
語言:Inglês
出版: BioMed Central 2005
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410760/
https://ncbi.nlm.nih.gov/pubmed/16457691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1345
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