Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis

INTRODUCTION: Metaplastic breast carcinomas constitute a heterogeneous group of neoplasms, accounting for less than 1% of all invasive mammary carcinomas. Approximately 70–80% of metaplastic breast carcinomas overexpress the epidermal growth factor receptor (EGFR). Human epidermal growth factor rece...

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Main Authors: Reis-Filho, Jorge S, Milanezi, Fernanda, Carvalho, Silvia, Simpson, Pete T, Steele, Dawn, Savage, Kay, Lambros, Maryou BK, Pereira, Emilio M, Nesland, Jahn M, Lakhani, Sunil R, Schmitt, Fernando C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410747/
https://ncbi.nlm.nih.gov/pubmed/16280056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1341
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