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Targeted therapy against Bcl-2-related proteins in breast cancer cells

INTRODUCTION: Bcl-2 and Bcl-xL confer resistance to apoptosis, thereby reducing the effectiveness of chemotherapy. We examined the relationship between the expression of Bcl-2 and Bcl-xL and chemosensitivity of breast cancer cells, with the aim of developing specific targeted therapy. METHODS: Four...

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Detalhes bibliográficos
Main Authors: Emi, Manabu, Kim, Ryungsa, Tanabe, Kazuaki, Uchida, Yoko, Toge, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410745/
https://ncbi.nlm.nih.gov/pubmed/16280040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1323
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