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A common missense variant in BRCA2 predisposes to early onset breast cancer
INTRODUCTION: Mutations in the BRCA2 gene are one of the two major causes of hereditary breast cancer. Protein-truncating mutations of BRCA2 are usually deleterious and increase the risk of breast cancer up to 80% over a lifetime. A few missense mutations in BRCA2 are believed to have a similarly hi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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BioMed Central
2005
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1410744/ https://ncbi.nlm.nih.gov/pubmed/16280055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1338 |
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