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The progestational and androgenic properties of medroxyprogesterone acetate: gene regulatory overlap with dihydrotestosterone in breast cancer cells

INTRODUCTION: Medroxyprogesterone acetate (MPA), the major progestin used for oral contraception and hormone replacement therapy, has been implicated in increased breast cancer risk. Is this risk due to its progestational or androgenic properties? To address this, we assessed the transcriptional eff...

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Detalhes bibliográficos
Main Authors: Ghatge, Radhika P, Jacobsen, Britta M, Schittone, Stephanie A, Horwitz, Kathryn B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410743/
https://ncbi.nlm.nih.gov/pubmed/16457685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1340
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