Complementary roles of intra- and extra-synaptic NMDA receptors in homeostatic synaptic plasticity?

Liu et al (Science, 304:1021-4) report that NMDA receptors containing NR2A and NR2B subunits are selectively coupled to long-term potentiation (LTP) and long-term depression (LTD) respectively. Because NR2B (but not NR2A) receptors occur outside synapses, and can be activated by glutamate spillover,...

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Hlavní autoři: Rusakov, Dmitri A, Scimemi, Annalisa, Walker, Matthew C, Kullmann, Dimitri M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410731/
https://ncbi.nlm.nih.gov/pubmed/15448254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1101128
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