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Complementary roles of intra- and extra-synaptic NMDA receptors in homeostatic synaptic plasticity?
Liu et al (Science, 304:1021-4) report that NMDA receptors containing NR2A and NR2B subunits are selectively coupled to long-term potentiation (LTP) and long-term depression (LTD) respectively. Because NR2B (but not NR2A) receptors occur outside synapses, and can be activated by glutamate spillover,...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1410731/ https://ncbi.nlm.nih.gov/pubmed/15448254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1101128 |
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