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WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl(−)-transporting epithelia
Mutations in WNK1 and WNK4, genes encoding members of a novel family of serine–threonine kinases, have recently been shown to cause pseudohypoaldosteronism type II (PHAII), an autosomal dominant disorder featuring hypertension, hyperkalemia, and renal tubular acidosis. The localization of these kina...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141053/ https://ncbi.nlm.nih.gov/pubmed/12522152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242728499 |
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