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CTCF functions as a critical regulator of cell-cycle arrest and death after ligation of the B cell receptor on immature B cells
The WEHI 231 B cell lymphoma is used as a model of self-tolerance by clonal deletion because B cell receptor (BCR) ligation results in apoptosis. Two critical events precede cell death: an early rise and fall in expression of MYC and cell-cycle arrest associated with enhanced expression of p21, p27,...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141048/ https://ncbi.nlm.nih.gov/pubmed/12524457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0237127100 |
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