Neoadjuvant Selective COX-2 Inhibition Down-Regulates Important Oncogenic Pathways in Patients With Esophageal Adenocarcinoma

OBJECTIVES: To evaluate the effects of neoadjuvant therapy with the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib in vitro and in patients with esophageal adenocarcinoma on COX-2 and MET expression. SUMMARY BACKGROUND DATA: High COX-2 and/or MET expression levels are negative prognostic fac...

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Main Authors: Tuynman, Jurriaan B., Buskens, Christianne J., Kemper, Kristel, ten Kate, Fiebo J. W., Offerhaus, G Johan A., Richel, Dirk J., van Lanschot, J Jan B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409886/
https://ncbi.nlm.nih.gov/pubmed/16327494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000189546.77520.ef
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