A Mutant Form of the Tax Protein of Bovine Leukemia Virus (BLV), with Enhanced Transactivation Activity, Increases Expression and Propagation of BLV In Vitro but Not In Vivo

In a previous study, we identified an interesting mutant form of the Tax protein of bovine leukemia virus (BLV), designated D247G. This mutant protein strongly transactivated the long terminal repeat of BLV and was also able to transactivate the cellular proto-oncogene c-fos. This finding suggested...

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Main Authors: Tajima, Shigeru, Takahashi, Masahiko, Takeshima, Shin-nosuke, Konnai, Satoru, Yin, Shan Ai, Watarai, Shinobu, Tanaka, Yoshimasa, Onuma, Misao, Okada, Kosuke, Aida, Yoko
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC140974/
https://ncbi.nlm.nih.gov/pubmed/12525624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.1894-1903.2003
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