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Sequential N- to C-terminal SNARE complex assembly drives priming and fusion of secretory vesicles

During exocytosis a four-helical coiled coil is formed between the three SNARE proteins syntaxin, synaptobrevin and SNAP-25, bridging vesicle and plasma membrane. We have investigated the assembly pathway of this complex by interfering with the stability of the hydrophobic interaction layers holding...

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Библиографические подробности
Главные авторы: Sørensen, Jakob B, Wiederhold, Katrin, Müller, Emil M, Milosevic, Ira, Nagy, Gábor, de Groot, Bert L, Grubmüller, Helmut, Fasshauer, Dirk
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409717/
https://ncbi.nlm.nih.gov/pubmed/16498411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601003
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