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Contribution of GIRK2-mediated postsynaptic signaling to opiate and α(2)-adrenergic analgesia and analgesic sex differences

The analgesia produced by inhibitory G protein-coupled receptor agonists involves coordinated postsynaptic inhibition via G protein-coupled inwardly rectifying potassium channels (GIRKs) and presynaptic inhibition of neurotransmitter release through regulation of voltage-gated Ca(2+) channels. Here,...

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Detalhes bibliográficos
Main Authors: Mitrovic, Igor, Margeta-Mitrovic, Marta, Bader, Semon, Stoffel, Markus, Jan, Lily Y., Basbaum, Allan I.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140949/
https://ncbi.nlm.nih.gov/pubmed/12496346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0136822100
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