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Synthetic antigens composed exclusively of L-or D-amino acids: II. Effect of optical configuration on the metabolism and fate of synthetic polypeptide antigens in mice

The immunogenic D-amino acid synthetic polypeptide, 247, p(D-Tyr, D-Glu, D-Ala), was shown to induce specific immunological paralysis in small doses in mice. The corresponding L-amino acid polypeptide, 253, p(L-Tyr, L-Glu, L-Ala) primes mice in similar doses. The metabolism and fate of these polymer...

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Bibliographische Detailangaben
Hauptverfasser: Janeway, C. A., Humphrey, J. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1968
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409293/
https://ncbi.nlm.nih.gov/pubmed/5640945
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