UDP-Glc:glycoprotein glucosyltransferase recognizes structured and solvent accessible hydrophobic patches in molten globule-like folding intermediates

Protein folding in the cell involves the action of different molecular chaperones and folding-facilitating enzymes. In the endoplasmic reticulum (ER), the folding status of glycoproteins is stringently controlled by a glucosyltranferase enzyme (GT) that creates monoglucosylated structures recognized...

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Bibliographic Details
Main Authors: Caramelo, Julio J., Castro, Olga A., Alonso, Leonardo G., de Prat-Gay, Gonzalo, Parodi, Armando J.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC140890/
https://ncbi.nlm.nih.gov/pubmed/12518055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262661199
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