Hepatitis C Virus RNA Synthesis in a Cell-Free System Isolated from Replicon-Containing Hepatoma Cells

A number of hepatitis C virus (HCV) proteins, including NS5B, the RNA-dependent RNA polymerase, were detected in membrane fractions from Huh7 cells containing autonomously replicating HCV RNA replicons. These membrane fractions were used in a cell-free system for the analysis of HCV RNA replication....

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Autors principals: Hardy, Richard W., Marcotrigiano, Joseph, Blight, Keril J., Majors, John E., Rice, Charles M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC140877/
https://ncbi.nlm.nih.gov/pubmed/12525637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.2029-2037.2003
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