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Crystal structure of saposin B reveals a dimeric shell for lipid binding
Saposin B is a small, nonenzymatic glycosphingolipid activator protein required for the breakdown of cerebroside sulfates (sulfatides) within the lysosome. The protein can extract target lipids from membranes, forming soluble protein-lipid complexes that are recognized by arylsulfatase A. The crysta...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140876/ https://ncbi.nlm.nih.gov/pubmed/12518053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0136947100 |
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