Adenovirus Type 5 DNA Binding Protein Stimulates Binding of DNA Polymerase to the Replication Origin

The adenovirus (Ad) DNA-binding protein (DBP) is essential for the elongation phase of Ad DNA replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers. DBP also enhances the rate of initiation, with the highest levels obtained at low concentration...

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Bibliographic Details
Main Authors: van Breukelen, Bas, Brenkman, Arjan B., Holthuizen, P. Elly, van der Vliet, Peter C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC140850/
https://ncbi.nlm.nih.gov/pubmed/12502807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.915-922.2003
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