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Recognition of Native Hepatitis C Virus E1E2 Heterodimers by a Human Monoclonal Antibody

The majority of hepatitis C virus (HCV)-infected individuals progress from acute to chronic disease, despite the presence of a strong humoral immune response to the envelope glycoproteins E1 and E2. When expressed in mammalian cells, E1 and E2 form both noncovalently linked E1E2 heterodimers, believ...

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Gepubliceerd in:J Virol
Hoofdauteurs: Cocquerel, Laurence, Quinn, Elizabeth R., Flint, Mike, Hadlock, Kenneth G., Foung, Steven K. H., Levy, Shoshana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2003
Onderwerpen:
Structure and Assembly
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140849/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12502876/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.2.1604-1609.2003
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