Antiviral Effect and Virus-Host Interactions in Response to Alpha Interferon, Gamma Interferon, Poly(I)-Poly(C), Tumor Necrosis Factor Alpha, and Ribavirin in Hepatitis C Virus Subgenomic Replicons

The recently developed hepatitis C virus (HCV) subgenomic replicon system was utilized to evaluate the efficacy of several known antiviral agents. Cell lines that persistently maintained a genotype 1b replicon were selected. The replicon resident in each cell line had acquired adaptive mutations in...

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Autori principali: Lanford, Robert E., Guerra, Bernadette, Lee, Helen, Averett, Devron R., Pfeiffer, Brad, Chavez, Deborah, Notvall, Lena, Bigger, Catherine
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC140845/
https://ncbi.nlm.nih.gov/pubmed/12502825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.1092-1104.2003
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