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EBNA3A Association with RBP-Jκ Down-Regulates c-myc and Epstein-Barr Virus-Transformed Lymphoblast Growth

Epstein-Barr virus nuclear antigen protein 3A (EBNA3A) is one of four EBNAs (EBNA-2, EBNALP, EBNA3A, and EBNA3C) through the cellular DNA sequence-specific transcription factor RBP-Jκ/CBF-1/CSL and are essential for conversion of primary B lymphocytes to lymphoblastoid cell lines (LCLs). In the pres...

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Udgivet i:J Virol
Principais autores: Cooper, Andrew, Johannsen, Eric, Maruo, Seiji, Cahir-McFarland, Ellen, Illanes, Diego, Davidson, David, Kieff, Elliott
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Transformation and Oncogenesis
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140836/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12502816/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.2.999-1010.2003
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