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Valency of Antibody Binding to Enveloped Virus Particles as Determined by Surface Plasmon Resonance

A simple method is described for determining the valency of binding of immunoglobulin G to immobilized influenza A virus. Where there is a free Fab arm (monovalent binding), a second virus particle is captured. This is detected by surface plasmon resonance. The methodology should be applicable to al...

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Detalhes bibliográficos
Main Authors: Hardy, Sam A., Dimmock, Nigel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140826/
https://ncbi.nlm.nih.gov/pubmed/12502884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.1649-1652.2003
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