A Protective Role of Locally Administered Immunostimulatory CpG Oligodeoxynucleotide in a Mouse Model of Genital Herpes Infection

Unmethylated CpG dinucleotides in bacterial DNA or synthetic oligodeoxynucleotides (ODNs) are known as potent activators of the immune system and inducers of several Th1-associated immunomodulatory cytokines. We therefore investigated whether such a CpG-containing ODN (CpG ODN) given mucosally in th...

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Autores principales: Harandi, Ali M., Eriksson, Kristina, Holmgren, Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC140825/
https://ncbi.nlm.nih.gov/pubmed/12502811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.953-962.2003
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