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Studies on immunological paralysis: V. The influence of molecular weight on the immunogenicity, tolerogenicity and antibody-neutralizing activity of type III pneumococcal polysaccharide

Type 3 pneumococcal polysaccharide (SIII) with average molecular weight 220,000 was depolymerized by heating aqueous solutions under pressure. The immunogenicity and tolerogenicity of fractions with molecular weights of 121,000, 31,000 and 4000 were compared with the native antigen by means of direc...

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Bibliographic Details
Main Authors: Howard, J. G., Zola, H., Christie, G. H., Courtenay, Barbara M.
Format: Artigo
Language:Inglês
Published: 1971
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1408154/
https://ncbi.nlm.nih.gov/pubmed/4398137
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