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Biosynthesis of the second (C2) and fourth (C4) components of complement in vitro by tissues isolated from guinea-pigs with genetically determined C4 deficiency

Tissues and cells isolated from guinea-pigs homozygous for a genetically determined deficiency of the fourth (C4) component of complement failed to synthesize C4 and synthesized C2 at a rate approximately 40 per cent of normal. These abnormalities in the biosynthesis of C2 and C4 persisted up to fou...

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Bibliographic Details
Main Authors: Colten, H. R., Frank, M. M.
Format: Artigo
Language:Inglês
Published: 1972
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1407873/
https://ncbi.nlm.nih.gov/pubmed/5032493
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