Construction of an Excisable Bacterial Artificial Chromosome Containing a Full-Length Infectious Clone of Herpes Simplex Virus Type 1: Viruses Reconstituted from the Clone Exhibit Wild-Type Properties In Vitro and In Vivo

In recent years, several laboratories have reported on the cloning of herpes simplex virus type 1 (HSV-1) genomes as bacterial artificial chromosomes (BACs) in Escherichia coli and on procedures to manipulate these genomes by using the bacterial recombination machinery. However, the HSV-BACs reporte...

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Autores principales: Tanaka, Michiko, Kagawa, Hiroyuki, Yamanashi, Yuji, Sata, Tetsutaro, Kawaguchi, Yasushi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC140785/
https://ncbi.nlm.nih.gov/pubmed/12502854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.1382-1391.2003
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