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Reactivation of Lytic Replication from B Cells Latently Infected with Epstein-Barr Virus Occurs with High S-Phase Cyclin-Dependent Kinase Activity while Inhibiting Cellular DNA Replication

Productive infection and replication of herpesviruses usually occurs in growth-arrested cells, but there has been no direct evidence in the case of Epstein-Barr virus (EBV), since an efficient lytic replication system without external stimuli does not exist for the virus. Expression of the EBV lytic...

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Détails bibliographiques
Auteurs principaux: Kudoh, Ayumi, Fujita, Masatoshi, Kiyono, Tohru, Kuzushima, Kiyotaka, Sugaya, Yutaka, Izuta, Shunji, Nishiyama, Yukihiro, Tsurumi, Tatsuya
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC140784/
https://ncbi.nlm.nih.gov/pubmed/12502801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.851-861.2003
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