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Antidepressants upregulate messenger RNA levels of the neuroprotective enzyme superoxide dismutase (SOD1).

OBJECTIVE: To investigate the effect of amitriptyline, bupropion, doxepin or venlafaxine on the gene expression of the neuroprotective enzyme superoxide dismutase (SOD1) in a catecholamine cell in vitro model. DESIGN: Molecular study of a cultured cell line. INTERVENTIONS: Rat pheochromocytoma (PC12...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, X M, Chlan-Fourney, J, Juorio, A V, Bennett, V L, Shrikhande, S, Bowen, R C
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1407692/
https://ncbi.nlm.nih.gov/pubmed/10721683
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