ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding

Aminoacyl-tRNA synthetases catalyze the formation of an aminoacyl-AMP from an amino acid and ATP, prior to the aminoacyl transfer to tRNA. A subset of aminoacyl-tRNA synthetases, including glutamyl-tRNA synthetase (GluRS), have a regulation mechanism to avoid aminoacyl-AMP formation in the absence o...

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Главные авторы: Sekine, Shun-ichi, Nureki, Osamu, Dubois, Daniel Y., Bernier, Stéphane, Chênevert, Robert, Lapointe, Jacques, Vassylyev, Dmitry G., Yokoyama, Shigeyuki
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC140737/
https://ncbi.nlm.nih.gov/pubmed/12554668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg053
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