The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation

The gastric pathogen Helicobacter pylori translocates the CagA protein into epithelial cells by a type IV secretion process. Translocated CagA is tyrosine phosphorylated (CagA(P-Tyr)) on specific EPIYA sequence repeats by Src family tyrosine kinases. Phos phorylation of CagA induces the dephosphoryl...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Selbach, Matthias, Moese, Stefan, Hurwitz, Robert, Hauck, Christof R., Meyer, Thomas F., Backert, Steffen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2003
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140734/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12554652/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg050
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