A model for dsDNA translocation revealed by a structural motif common to RecG and Mfd proteins

RecG protein differs from other helicases analysed to atomic resolution in that it mediates strand separation via translocation on double-stranded (ds) rather than single-stranded (ss) DNA. We describe a highly conserved helical hairpin motif in RecG and show it to be important for helicase activity...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Mahdi, Akeel A., Briggs, Geoffrey S., Sharples, Gary J., Wen, Qin, Lloyd, Robert G.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2003
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140728/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12554672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg043
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