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Restriction of multiple divergent retroviruses by Lv1 and Ref1

The mouse gene Fv1 encodes a saturable restriction factor that selectively blocks infection by N-tropic or B-tropic murine leukemia virus (MLV) strains. Despite the absence of an Fv1 gene, a similar activity is present in humans that blocks N-MLV infection (Ref1). Moreover, some non-human primate ce...

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Main Authors: Hatziioannou, Theodora, Cowan, Simone, Goff, Stephen P., Bieniasz, Paul D., Towers, Greg J.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC140727/
https://ncbi.nlm.nih.gov/pubmed/12554640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg042
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