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Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin–ICAM-2 complex

ERM (ezrin/radixin/moesin) proteins recognize the cytoplasmic domains of adhesion molecules in the formation of the membrane-associated cytoskeleton. Here we report the crystal structure of the radixin FERM (4.1 and ERM) domain complexed with the ICAM-2 cytoplasmic peptide. The non-polar region of t...

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Autors principals: Hamada, Keisuke, Shimizu, Toshiyuki, Yonemura, Shigenobu, Tsukita, Shoichiro, Tsukita, Sachiko, Hakoshima, Toshio
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC140724/
https://ncbi.nlm.nih.gov/pubmed/12554651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg039
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