A Ral Guanine Exchange Factor-Ral Pathway Is Conserved in Drosophila melanogaster and Sheds New Light on the Connectivity of the Ral, Ras, and Rap Pathways

Ras GTPases are central to many physiological and pathological signaling pathways and act via a combination of effectors. In mammals, at least three Ral exchange factors (RalGEFs) contain a Ras association domain and constitute a discrete subgroup of Ras effectors. Despite their ability to bind acti...

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Bibliographic Details
Main Authors: Mirey, Gladys, Balakireva, Maria, L'Hoste, Sébastien, Rossé, Carine, Voegeling, Stéphanie, Camonis, Jacques
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC140692/
https://ncbi.nlm.nih.gov/pubmed/12529414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.3.1112-1124.2003
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