Mutations in Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Causing Increased Receptor Binding Activity and Resistance to the Transition State Sialic Acid Analog 4-GU-DANA (Zanamivir)

Entry and fusion of human parainfluenza virus type 3 (HPF3) require the interaction of the viral hemagglutinin-neuraminidase (HN) glycoprotein with its sialic acid receptor. 4-GU-DANA, a potent inhibitor of influenza virus neuraminidase, inhibits not only HPF3 neuraminidase but also the receptor bin...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Murrell, Matthew, Porotto, Matteo, Weber, Thomas, Greengard, Olga, Moscona, Anne
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477836/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.1.309-317.2003
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!