CD8(+) T Cells Mediate Viral Clearance and Disease Pathogenesis during Acute Hepatitis B Virus Infection

Although the CD4(+)- and CD8(+)-T-cell responses to the hepatitis B virus (HBV) are thought to be crucial for the control of HBV infection, the relative contribution of each T-cell subset as an effector of viral clearance is not known. To examine this question, we monitored the course of HBV infecti...

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Main Authors: Thimme, Robert, Wieland, Stefan, Steiger, Carola, Ghrayeb, John, Reimann, Keith A., Purcell, Robert H., Chisari, Francis V.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC140637/
https://ncbi.nlm.nih.gov/pubmed/12477811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.68-76.2003
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