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NUCLEOPORINS NPP-1, NPP-3, NPP-4, NPP-11 and NPP-13 ARE REQUIRED FOR PROPER SPINDLE ORIENTATION IN C. ELEGANS

Nucleoporins are components of the nuclear pore, which is required for nucleo-cytoplasmic transport. We report a role for a subclass of nucleoporins in orienting the mitotic spindle in C. elegans embryos. RNAi-mediated depletion of any of five putative nucleoporins npp-1, npp-3, npp-4, npp-11, and n...

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Bibliographic Details
Main Authors: Schetter, Aaron, Askjaer, Peter, Piano, Fabio, Mattaj, Iain, Kemphues, Kenneth
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1405919/
https://ncbi.nlm.nih.gov/pubmed/16325795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2005.10.038
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