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Disruption of Mitochondrial Networks by the Human Cytomegalovirus UL37 Gene Product Viral Mitochondrion-Localized Inhibitor of Apoptosis

By 24 h after infection with human cytomegalovirus, the reticular mitochondrial network characteristic of uninfected fibroblasts was disrupted as mitochondria became punctate and dispersed. These alterations were associated with expression of the immediate-early (α) antiapoptotic UL37x1 gene product...

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Main Authors: McCormick, A. Louise, Smith, Vanessa L., Chow, Dar, Mocarski, Edward S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC140587/
https://ncbi.nlm.nih.gov/pubmed/12477866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.631-641.2003
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