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Temperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome

Rrp43p is a Saccharomyces cerevisiae exosome subunit involved in pre-rRNA processing which is found both in the nucleus and in the cytoplasm. So far, no function has been assigned to the cytoplasmic fraction of Rrp43p. We have addressed Rrp43p function by analyzing mRNA stability in three rrp43 temp...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Oliveira, Carla C., Gonzales, Fernando A., Zanchin, Nilson I. T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140545/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12364597/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf545
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