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Cellular uptake of Antennapedia Penetratin peptides is a two-step process in which phase transfer precedes a tryptophan-dependent translocation

Several homeodomains and homeodomain-containing proteins enter live cells through a receptor- and energy-independent mechanism. Translocation through biological membranes is conferred by the third α-helix of the homeodomain, also known as Penetratin. Biophysical studies demonstrate that entry of Pen...

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Main Authors: Dom, Geneviève, Shaw-Jackson, Chloë, Matis, Christelle, Bouffioux, Olivier, Picard, Jacques J., Prochiantz, Alain, Mingeot-Leclercq, Marie-Paule, Brasseur, Robert, Rezsohazy, René
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC140524/
https://ncbi.nlm.nih.gov/pubmed/12527762
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