Delayed radioprotection by nuclear transcription factor κB -mediated induction of manganese superoxide dismutase in human microvascular endothelial cells after exposure to the free radical scavenger WR1065

The free radical scavenger WR1065 (SH) is the active thiol form of the clinically approved cytoprotector amifostine. At doses of 40 μM and 4 mM it can activate the redox-sensitive nuclear transcription factor κB (NFκB) and elevate the expression of the antioxidant gene manganese superoxide dismutase...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Murley, Jeffrey S., Kataoka, Yasushi, Weydert, Christine J., Oberley, Larry W., Grdina, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1405236/
https://ncbi.nlm.nih.gov/pubmed/16540396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2005.10.060
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky