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Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells

The post-transcriptional gene silencing in animals and plants is called RNA interference (RNAi). Guides for the sequence-specific degradation of mRNA are 21-nt small interfering RNAs (siRNAs) that are generated by Dicer-dependent cleavage from longer double-stranded RNAs (dsRNAs). To examine the rel...

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Bibliografiska uppgifter
Huvudupphovsmän: Kawasaki, Hiroaki, Taira, Kazunari
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC140522/
https://ncbi.nlm.nih.gov/pubmed/12527779
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