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Function of Extracellular Loop 2 in Rhodopsin: Glutamic Acid 181 Modulates Stability and Absorption Wavelength of Metarhodopsin II

The second extracellular loop of rhodopsin folds back into the membrane-embedded domain of the receptor to form part of the binding pocket for the 11-cis-retinylidene chromophore. A carboxylic acid side chain from this loop, Glu181, points toward the center of the retinal polyene chain. We studied t...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Yan, Elsa C. Y., Kazmi, Manija A., De, Soma, Chang, Belinda S. W., Seibert, Christoph, Marin, Ethan P., Mathies, Richard A., Sakmar, Thomas P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2002
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1404524/
https://ncbi.nlm.nih.gov/pubmed/11888278
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