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Ribozyme-Mediated Perlecan Knockdown Impairs Chondrogenic Differentiation of C3H10T1/2 Fibroblasts
Perlecan (Pln) is an abundant heparan sulfate (HS) proteoglycan in the pericellular matrix of developing cartilage, and its absence dramatically disrupts endochondral bone formation. This study examined two previously unexamined aspects of the function of Pln in mesenchymal chondrogenesis in vitro....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1403289/ https://ncbi.nlm.nih.gov/pubmed/16466400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1432-0436.2005.00055.x |
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