Less Efficient G(2)-M Checkpoint Is Associated with an Increased Risk of Lung Cancer in African Americans

Cell cycle checkpoints play critical roles in the maintenance of genomic integrity. The inactivation of checkpoint genes by genetic and epigenetic mechanisms is frequent in all cancer types, as a less-efficient cell cycle control can lead to genetic instability and tumorigenesis. In an on-going case...

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Main Authors: Zheng, Yun-Ling, Loffredo, Christopher A., Alberg, Anthony J., Yu, Zhipeng, Jones, Raymond T., Perlmutter, Donna, Enewold, Lindsey, Krasna, Mark J., Yung, Rex, Shields, Peter G., Harris, Curtis C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1403288/
https://ncbi.nlm.nih.gov/pubmed/16230422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-1003
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