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Expression of UDP-Glucuronosyltransferase Isoform mRNAs during Inflammation and Infection in Mouse Liver and Kidney
Inflammation or infection down-regulate the activity and expression of cytochrome P450 (P450) enzymes involved in hepatic drug clearance, possibly altering drug effectiveness and leading to toxicity. The regulation of UDP-glucuronosyltransferases (UGTs) in inflammation and infection is less well cha...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1403152/ https://ncbi.nlm.nih.gov/pubmed/16339353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.105.007435 |
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