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Regulation of Vascular Endothelial Growth Factor Receptor-2 Activity by Caveolin-1 and Plasma Membrane Cholesterol

The stimulation of vascular endothelial growth factor receptor-2 (VEGFR-2) by tumor-derived VEGF represents a key event in the initiation of angiogenesis. In this work, we report that VEGFR-2 is localized in endothelial caveolae, associated with caveolin-1, and that this complex is rapidly dissociat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Labrecque, Lyne, Royal, Isabelle, Surprenant, David S., Patterson, Cam, Gingras, Denis, Béliveau, Richard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC140249/
https://ncbi.nlm.nih.gov/pubmed/12529448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-07-0379
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