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Rate of elimination of tracer doses of phenytoin at different steady-state serum phenytoin concentrations in epileptic patients

1 Serum phenytoin concentration, the serum half-life of a tracer dose of carbon-labelled phenytoin, and the ratio of the major metabolite of phenytoin to unchanged drug in urine (p-HPPH: DPH ratio) were measured in epileptic patients on chronic anticonvulsant therapy. 2 A significant correlation was...

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Detalhes bibliográficos
Main Authors: Houghton, G. W., Richens, A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402453/
https://ncbi.nlm.nih.gov/pubmed/22454903
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