Kinetics of isosorbide dinitrate and relationships to pharmacological effects.

1 The inter-relationships among oral isosorbide dinitrate (ISDN) dose, drug pharmacokinetics and pharmacological effects were studied in 12 angina patients following single and chronic doses of 15, 30, 60 and 120 mg. 2 Significant accumulation of intact ISDN in plasma was observed after four times a...

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Bibliografiske detaljer
Main Authors: Fung, H L, McNiff, E F, Ruggirello, D, Darke, A, Thadani, U, Parker, J O
Format: Artigo
Sprog:Inglês
Udgivet: 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402196/
https://ncbi.nlm.nih.gov/pubmed/7272174
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